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Aranesp

Aranesp is an an erythropoiesis-stimulating agent (ESA) manufactured by Amgen.  It is used to treat anemia in patients who have undergone kidney failure or have developed anemia as the result of chemotherapy treatment.  In March 2007, the federal Food and Drug Administration (FDA) issued a health advisory regarding ESAs, including Procrit, Epogen and Aranesp, pointing to studies that show a risk of stroke, heart attack, or death for patients with renal failure when hemoglobin levels are raised higher than indicated. 

Fast Facts

Name: Aranesp
Generic: Darbepoetin alfa
Manufacturer: Amgen
Date approved: July 2002
Status: Public health advisory and "Dear Doctor letter"
Approved uses: Treatment of kidney failure-related anemia and anemia due to chemotherapy
Off-Label uses: N/A
Side effects: Heart attack, stroke, death. Minor side effects include headache, fever, joint pain, and gastrointestinal distress.
Related topics: Procrit, Epogen

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Jury Verdicts Related to Aranesp

______ VERDICT Alleged breach of contract - Failure of physician to pay 10% "restocking" fee for "overstocked" returned product.

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FDA Information Related to Aranesp

Information for Healthcare Professionals: Erythropoiesis Stimulating Agents (ESA)

Communication about an Ongoing Safety Review: Erythropoiesis-Stimulating Agents (ESAs)

View the Aranesp FDA Information page here


MSN Newsfeeds Related to Aranesp

Mayo Clinic Study Links Anemia Drugs to Leukemia Risk

Fresh concerns about Amgen's anemia drugs

View the Aranesp MSN Newsfeeds page here


News Articles Related to Aranesp

Claude Resources Inc. raises total of $18.1 million with debenture

AKES: Dr. Carl LeBel Named Pres and COO; Dr. Jay Lichter Remains CEO

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Patents Related to Aranesp

Production of erythropoietin

View the Aranesp Patents page here


Wikipedia Entries Related to Aranesp

Erythropoietin

Darbepoetin alfa

View the Aranesp Wikipedia Entries page here


Books Related to Aranesp

Amgen executive angered over coverage restrictions: CMS won't pay for anemia treatment, which means fewer Aranesp sales.(BIOTECH): An article from: Los Angeles Business Journal

Amgen falls Ill from Medicare payment shifts.: An article from: Los Angeles Business Journal

View the Aranesp Books page here

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